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FAK(Phospho Tyr577) Polyclonal Antibody, 50ul Liquid Handling &Storage Cleavage of the precursor generates

SKU: 61336067720

4.1
DKK185.00 DKK235.00

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FAK(Phospho Tyr577) Polyclonal Antibody, 50ul Liquid Handling &Storage Cleavage of the precursor generatesThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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Description

Cleavage of the precursor generates alpha and beta subunits

PKC family members also serve as major receptors for phorbol esters

An important paralog of this gene is HSH2D

|PTM:Monomethylation at Arg-4 by PRMT1 favors acetylation at Lys-9 and Lys-13

Mutations in this gene can result in B cell deficiency and agammaglobulinemia

FAK(Phospho Tyr577) Polyclonal Antibody, 50ul Liquid Handling &Storage Cleavage of the precursor generatesThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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