Caspase-4 Polyclonal Antibody, 50ul Cell Senescence Allelic variants of this gene

Allelic variants of this gene have been associated with nicotine dependence

Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis

The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis

Mutations in this gene are associated with susceptibility to essential hypertension

Alternative splicing results in multiple transcript variants of ACVR2A

Caspase-4 Polyclonal Antibody, 50ul Cell Senescence Allelic variants of this geneCASP4 (caspase 4) encodes a protein that is a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of