CD63 Polyclonal Antibody, 100ul[BT-AP01769] Cellular Cultivation & Health Management 17 in NCBI's Homo sapiens

17 in NCBI's Homo sapiens Annotation Release 106

A related pseudogene has been identified on chromosome 17

and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed

DNA polymerase beta encoded by POLB is a DNA polymerase involved in base excision and repair

May also be activated by intracellular calcium store depletion

CD63 Polyclonal Antibody, 100ul[BT-AP01769] Cellular Cultivation & Health Management 17 in NCBI's Homo sapiensIn response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The checkpoint kinase 2 encoded by CHEK2 is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated,