GP183 Polyclonal Antibody, 50ul Measuring Instruments The encoded protein contains a

The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site| and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton| possibly by direct association with actin or spectrin

In these bifunctional molecules

The encoded protein has also been shown to transport anticancer drugs like bleomycin (PMID: 20037140) successful treatment has been correlated with the level of activity of this transporter in tumor cells

Present in lymphocytes (at protein level)

and a 40-kD subunit that is a member of the cytokine receptor family

GP183 Polyclonal Antibody, 50ul Measuring Instruments The encoded protein contains aThis gene was identified by the up regulation of its expression upon Epstein Barr virus infection of primary B lymphocytes. This gene is predicted to encode a G protein coupled receptor that is most closely related to the thrombin receptor. Expression of this gene was detected in B lymphocyte cell lines and lymphoid tissues but not in T lymphocyte cell lines or peripheral blood T lymphocytes. The function of this gene is unknown.