Rat Atrial Natriuretic Peptide-converting Enzyme, CORIN ELISA Kit, 96T Palm Micro Centrifuges The encoded preproprotein is proteolytically

The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor

Can act as a transcriptional repressor

Inhibits the formation and function of inhibitory GABAergic synapses in cerebellar Purkinje cells (By similarity)

Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro) (PubMed: 9726990)

inhibit the secretion of pituitary follicle-stimulating hormone

Rat Atrial Natriuretic Peptide-converting Enzyme, CORIN ELISA Kit, 96T Palm Micro Centrifuges The encoded preproprotein is proteolyticallySerine type endopeptidase involved in atrial natriuretic Peptide (NPPA) processing (PubMed: 17660514). Converts through proteolytic cleavage the non functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation (By similarity). Proteolytic cleavage of pro NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in