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A20 Polyclonal Antibody, 100ul[BT-AP00064] Mechanical Pipette ATAD3A and ATAD3B (MIM 612317)

SKU: 593992101

4.8
USD141.00 USD188.00

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A20 Polyclonal Antibody, 100ul[BT-AP00064] Mechanical Pipette ATAD3A and ATAD3B (MIM 612317)TNFAIP3 was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). TNF alpha induced protein 3 encoded by TNFAIP3 is a zinc finger protein and ubiqitin editing enzyme, and has been shown to inhibit NF kappa B activation as well as TNF mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine mediated immune and inflammatory responses.

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Description

ATAD3A and ATAD3B (MIM 612317) are mitochondrial membrane proteins that contribute to the stabilization of large mitochondrial DNA (mtDNA)-protein complexes called nucleoids (He et al

Binding of these ligands to the receptor activates several signal transduction pathways

the interaction inhibits p105 processing into p50

Increased expression of this gene may be linked to psoriasis

Members of PAX8 family typically encode proteins that contain a paired box domain

A20 Polyclonal Antibody, 100ul[BT-AP00064] Mechanical Pipette ATAD3A and ATAD3B (MIM 612317)TNFAIP3 was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). TNF alpha induced protein 3 encoded by TNFAIP3 is a zinc finger protein and ubiqitin editing enzyme, and has been shown to inhibit NF kappa B activation as well as TNF mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine mediated immune and inflammatory responses.

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