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Ret Monoclonal Antibody, 100ul[BT-MCA1097] Immune Repertoire Sequencing Two transcript variants encoding different

SKU: 590825225

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Ret Monoclonal Antibody, 100ul[BT-MCA1097] Immune Repertoire Sequencing Two transcript variants encoding differentThis gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine

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Description

Two transcript variants encoding different isoforms have been found for GNPAT

FANCM and FANCN (also called PALB2)

The encoded protein is found in the cytoplasm as part of a multiprotein complex

subunit:When phosphorylated

Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway

Ret Monoclonal Antibody, 100ul[BT-MCA1097] Immune Repertoire Sequencing Two transcript variants encoding differentThis gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine

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