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4E-BP1(Phospho Ser65) Polyclonal Antibody, 50ul Plasma functions as guanine nucleotide exchange

SKU: 58716327886

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4E-BP1(Phospho Ser65) Polyclonal Antibody, 50ul Plasma functions as guanine nucleotide exchangeThis gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E) which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV

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Description

functions as guanine nucleotide exchange factor

It is very similar to the family member HNRPH1

• Speed up to 15000rpm

Mutations at this locus have been associated with microcephaly

and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR

4E-BP1(Phospho Ser65) Polyclonal Antibody, 50ul Plasma functions as guanine nucleotide exchangeThis gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E) which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV

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