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Flt-4 Polyclonal Antibody, 20ul[BT-AP15638] Serum TOP2A encoding this enzyme functions

SKU: 57344985587

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Flt-4 Polyclonal Antibody, 20ul[BT-AP15638] Serum TOP2A encoding this enzyme functionsThis gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA.

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Description

TOP2A encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance

Sterols inhibit the cleavage of the precursor| and the mature nuclear form is rapidly catabolized| thereby reducing transcription

T and B lymphocytes

NF-κB1 (p105/p50)

and intracellularly a protein kinase homology domain

Flt-4 Polyclonal Antibody, 20ul[BT-AP15638] Serum TOP2A encoding this enzyme functionsThis gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA.

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