BMP-8B Polyclonal Antibody, 100ul Immune Cell Preparation Mutations in this gene are

Mutations in this gene are associated with congenital cataracts| facial dysmorphism and neuropathy syndrome (CCFDN)

The encoded protein is involved in many cellular processes

a group of transcription factors regulated by small hydrophobic hormones

with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane

Among its related pathways are Phase II conjugation and Metabolism

BMP-8B Polyclonal Antibody, 100ul Immune Cell Preparation Mutations in this gene areBMP8B encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue.