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PTEN mouse Monoclonal Antibody(9E8), 50ul Cell Culture This protein may be involved

SKU: 57179020164

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PTEN mouse Monoclonal Antibody(9E8), 50ul Cell Culture This protein may be involvedThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide

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Description

This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication

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but they are not thought to encode a fusion protein

It inhibits PDGF-induced membrane ruffling mediated by Rac

The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration

PTEN mouse Monoclonal Antibody(9E8), 50ul Cell Culture This protein may be involvedThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide

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