HEXI2 Polyclonal Antibody, 100ul Micro Centrifuge Tubes PH domain binds phospholipids including

PH domain binds phospholipids including phosphatidic acid| phosphatidylinositol 3-phosphate| phosphatidylinositol 3|5-bisphosphate (PIP2) and phosphatidylinositol 3|4|5-trisphosphate (PIP3)

Mutations in this gene are associated with slow-channel congenital myasthenic syndrome

which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein

Multiple alternatively spliced transcript variants for RSU1 have been reported

The protein encoded by this gene belongs to the GSK-3-binding protein family

HEXI2 Polyclonal Antibody, 100ul Micro Centrifuge Tubes PH domain binds phospholipids includingThis gene encodes a member of the HEXIM family of proteins. This protein is a component of the 7SK small nuclear ribonucleoprotein. This protein has been found to negatively regulate the kinase activity of the cyclin dependent kinase P TEFb, which phosphorylates multiple target proteins to promote transcriptional elongation. This gene is located approximately 7 kb downstream from related family member HEXIM1 on chromosome 17. Alternative splicing