CYR61 Polyclonal Antibody, 20ul sgRNA Library Construction Members of the connecdenn family|

Members of the connecdenn family| such as DENND1A| function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2

sensorineural deafness

Present in T-cells but not B-cells (at protein level)

and it is abrogated by mutations in the pleckstrin homology domain of AKT1

Alternatively spliced transcript variants have been described for this gene

CYR61 Polyclonal Antibody, 20ul sgRNA Library Construction Members of the connecdenn family|The secreted protein encoded by this gene is growth factor inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate proteoglycan. This protein also plays a role in cell proliferation, differentiation, angiogenesis, apoptosis, and extracellular matrix formation.