POGK Rabbit Polyclonal Antibody, 50ul Primary Antibodies Carboxypeptidase N is a plasma

Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins

playing a role in T-cell and B-cell development and activation

Mutation analysis of this gene has not revealed any mutation which causes the CPX disorder

Thr-538 (activation loop of the kinase domain)| Ser-676 (turn motif) and Ser-695 (hydrophobic region)| need to be phosphorylated for its full activation

There are multiple pseudogenes of RPL10 dispersed throughout the genome

POGK Rabbit Polyclonal Antibody, 50ul Primary Antibodies Carboxypeptidase N is a plasmaThe exact function of the protein encoded by this gene is not known. However this gene product contains a KRAB domain (which is involved in protein protein interactions) at the N terminus and a transposase domain at the C terminus suggesting that it may belong to the family of DNA mediated transposons in human.