SHIP-2 Polyclonal Antibody, 100ul Protein Post-translational Modification Mutations in this gene cause

Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III)

The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation

Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides

congenital heart disease and other features

Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor

SHIP-2 Polyclonal Antibody, 100ul Protein Post-translational Modification Mutations in this gene causePhosphatidylinositol 3,4,5 trisphosphate 5 phosphatase 2 encoded by INPPL1 is an SH2 containing 5' inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.