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Arrestin-C Polyclonal Antibody, 50ul Lentiviral Packaging May be involved in transmitting

SKU: 56245654206

4.1
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Arrestin-C Polyclonal Antibody, 50ul Lentiviral Packaging May be involved in transmittingThe protein encoded by ARR3 is a non visual arrestin which binds to agonist activated, phosphorylated G protein coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma tubulin to help regulate proper centrosome function.

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Description

May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell

This gene encodes an alpha subunit that is widely expressed in the brain

and mRNA localization

Additional variants have been

is related to mutations in the ALMS1 gene

Arrestin-C Polyclonal Antibody, 50ul Lentiviral Packaging May be involved in transmittingThe protein encoded by ARR3 is a non visual arrestin which binds to agonist activated, phosphorylated G protein coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma tubulin to help regulate proper centrosome function.

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