Cot(Phospho Ser400) Polyclonal Antibody, 50ul Mammalian Expression The protein encoded by this

The protein encoded by this gene belongs to the Fbxs class and it contains an F-box domain

Alternate start codons result in two isoforms of the protein

Mutations in this gene are associated with the autosomal dominant disorder

E3 ubiquitin-protein ligase Mdm2 can promote tumor formation by targeting tumor suppressor proteins

such as RAL

Cot(Phospho Ser400) Polyclonal Antibody, 50ul Mammalian Expression The protein encoded by thisThis gene is an oncogene that encodes a member of the serine threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF kappaB. This protein was also found to promote the production of TNF alpha and IL 2 during T lymphocyte activation. This gene may also utilize a downstream