Neu Polyclonal Antibody, 100ul[BT-AP05900] Peripheral Blood Separation Tube Functions in nuclear protein import

Functions in nuclear protein import as nuclear transport receptor

Alternative splicing of this gene results in two transcript variants

forms the DNA polymerase alpha complex

characterized by proteinuria

Mutations in this gene cause hereditary neuralgic amyotrophy

Neu Polyclonal Antibody, 100ul[BT-AP05900] Peripheral Blood Separation Tube Functions in nuclear protein importERBB2 encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Receptor tyrosine protein kinase erbB 2 has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those