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PACRG Rabbit Polyclonal Antibody, 100ul Gene Synthesis APP encodes a cell surface

SKU: 56100590031

4.1
PLN123.75 PLN159.75

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PACRG Rabbit Polyclonal Antibody, 100ul Gene Synthesis APP encodes a cell surfaceThis gene encodes a protein that is conserved across metazoans. In vertebrates this gene is linked in a head to head arrangement with the adjacent parkin gene which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co regulated in various tissues and they share a bi directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co regulated gene protein forms a large molecular complex with

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Description

APP encodes a cell surface receptor and transmembrane precursor protein (amyloid beta precursor protein) that is cleaved by secretases to form a number of peptides

The gamma subunit also includes the skeletal muscle and hepatic isoforms| which are encoded by two different genes

It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues

This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression

This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL)

PACRG Rabbit Polyclonal Antibody, 100ul Gene Synthesis APP encodes a cell surfaceThis gene encodes a protein that is conserved across metazoans. In vertebrates this gene is linked in a head to head arrangement with the adjacent parkin gene which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co regulated in various tissues and they share a bi directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co regulated gene protein forms a large molecular complex with

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