RSPO4 Rabbit Polyclonal Antibody, 100ul Plasma attached to the plasma membrane

attached to the plasma membrane via a glycosylphosphatidyl inositol anchor

in contrast to the other GAP1 family members

The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways

It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein

and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation

RSPO4 Rabbit Polyclonal Antibody, 100ul Plasma attached to the plasma membraneThis gene encodes a member of the R spondin family of proteins that share a common domain organization consisting of a signal peptide cysteine rich furin like domain thrombospondin domain and a C terminal basic region. The encoded protein may be involved in activation of Wnt beta catenin signaling pathways. Mutations in this gene are associated with anonychia congenital. Alternate splicing results in multiple transcript variants.