PXK Rabbit Polyclonal Antibody, 20ul Pipette Micro Tips Histidine--tRNA ligase cytoplasmic encoded by

Histidine--tRNA ligase cytoplasmic encoded by HARS is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases

and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane

The encoded protein may play a role in the compaction| stabilization| and maintenance of myelin sheaths| as well as in oligodendrocyte development and axonal survival

Component of the cytosolic iron-sulfur protein assembly (CIA) complex

A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13

PXK Rabbit Polyclonal Antibody, 20ul Pipette Micro Tips Histidine--tRNA ligase cytoplasmic encoded byThis gene encodes a phox (PX) domain containing protein which may be involved in synaptic transmission and the ligand induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants.