Phospho-Amyloid-Beta (T743) Polyclonal Antibody, 100ul Deep Well Plates Mutations in this gene have

Mutations in this gene have been associated with increased severity of pseudoxanthoma elasticum

This gene location is also the candidate region of two different neurologic diseases: early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3)

and they have a greater tendency to allow potassium to flow into the cell rather than out of it

The SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses

May regulate SIAH1 activity

Phospho-Amyloid-Beta (T743) Polyclonal Antibody, 100ul Deep Well Plates Mutations in this gene haveAPP encodes a cell surface receptor and transmembrane precursor protein (amyloid beta precursor protein) that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1 TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are