FKRP Polyclonal Antibody, 100ul 3D Cell Culture Consumables fetal liver

fetal liver

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell

These proteins are found on cell membranes and serve as the targets for V-SNARES (vesicle-SNAP receptors) permitting specific synaptic vesicle docking and fusion

FLRTs may function in cell adhesion and/or receptor signalling

Defects in this gene are a cause of branchiooculofacial syndrome (BOFS)

FKRP Polyclonal Antibody, 100ul 3D Cell Culture Consumables fetal liverFKRP (fukutin related protein) encodes a protein which is targeted to the medial Golgi apparatus and is necessary for posttranslational modification of dystroglycan. Mutations in FKRP have been associated with congenital muscular dystrophy, mental retardation, and cerebellar cysts. Several alternatively spliced transcript variants of FKRP have been described, but the full length nature of some of these variants has not been determined.