SENP1 Polyclonal Antibody, 100ul Monoclonal Antibodies functions as a structural scaffold

functions as a structural scaffold to bring two clusters of positive-charged residues within spatial proximity to mimic a bipartite nuclear localization signal (NLS)

Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2)

This enzyme has an important role in MHC class II-restricted antigen processing

Mutations in SLC5A1 have been associated with glucose-galactose malabsorption

and a coiled-coil region

SENP1 Polyclonal Antibody, 100ul Monoclonal Antibodies functions as a structural scaffoldSENP1 encodes a cysteine protease that specifically targets members of the small ubiquitin like modifier (SUMO) protein family. This protease regulates SUMO pathways by deconjugating sumoylated proteins. This protease also functions to process the precursor SUMO proteins into their mature form. Alternate splicing results in multiple transcript variants.