hnRNP K(Phospho Ser284) Polyclonal Antibody, 20ul Serum & Sample Tubes A translocation involving this gene

A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene| encoding a DNA binding protein| located on chromosome 11 is associated with leukemia

and thus induce cell cycle arrest

The encoded protein also has phospholipase C activity

KLKB1 encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation

but can also be detected in other tissues

hnRNP K(Phospho Ser284) Polyclonal Antibody, 20ul Serum & Sample Tubes A translocation involving this geneThis gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre mRNAs in the nucleus and appear to influence pre mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus