IKK Alpha Monoclonal Antibody, 100ul[BT-MCA0104] Organelle Studies Down-regulates PDPK1 kinase activity by

Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues

muscleprovided by is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP

Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease

The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues

FGFR1OP encodes a largely hydrophilic centrosomal protein

IKK Alpha Monoclonal Antibody, 100ul[BT-MCA0104] Organelle Studies Down-regulates PDPK1 kinase activity byThis gene encodes a member of the serine threonine protein kinase family. The encoded protein, a component of a cytokine activated protein complex that is an inhibitor of the essential transcription factor NF kappa B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.