PKI Beta Polyclonal Antibody, 50ul Site-directed Mutagenesis Autoantibodies to the encoded protein

Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis

V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting| zymogen activation| receptor-mediated endocytosis| and synaptic vesicle proton gradient generation

Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death

This protein does not contain a coiled coil region like some family members| and its exact function is unknown

PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes

PKI Beta Polyclonal Antibody, 50ul Site-directed Mutagenesis Autoantibodies to the encoded proteinPKIB (protein kinase (cAMP dependent, catalytic) inhibitor beta) encodes a member of the cAMP dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of PKIB may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PKIB.