PEA-15 Polyclonal Antibody, 100ul[BT-AP07044] miRNA / siRNA Synthesis ARHGEF10 encodes a Rho guanine

ARHGEF10 encodes a Rho guanine nucleotide exchange factor (GEF)

The protein encoded by ACO1 has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions

The enzyme is found in nearly all cells capable of oxidative metablism

subunit:Homotrimer or homotetramer

Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy

PEA-15 Polyclonal Antibody, 100ul[BT-AP07044] miRNA / siRNA Synthesis ARHGEF10 encodes a Rho guaninePEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.