ARAP1 Polyclonal Antibody, 20ul Immune Repertoire Sequencing glomerulocystic kidney disease with hyperuricemia

glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI)

This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor

Unlike most MMPs

An important paralog of this gene is ZNF70

Contains 1 VHS domain

ARAP1 Polyclonal Antibody, 20ul Immune Repertoire Sequencing glomerulocystic kidney disease with hyperuricemiaThe protein encoded by this gene contains SAM, ARF GAP, RHO GAP, ankyrin repeat, RAS associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3) dependent ARF GAP activity. The encoded protein associates with the Golgi, and the ARF GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell specific trafficking of a