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Huntingtin(Phospho Ser421) Polyclonal Antibody, 100ul Vector Construction This factor undergoes multiple processing

SKU: 54224986316

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Huntingtin(Phospho Ser421) Polyclonal Antibody, 100ul Vector Construction This factor undergoes multiple processingHuntingtin is a disease gene linked to Huntington's disease, a neurodegenerative disorder characterized by loss of striatal neurons. This is thought to be caused by an expanded, unstable trinucleotide repeat in the huntingtin gene, which translates as a polyglutamine repeat in the protein product. A fairly broad range of trinucleotide repeats (9 35) has been identified in normal controls, and repeat numbers in excess of 40 have been described as

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Description

This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR

in cytomegalovirus-infected cells

N-linked glycoprotein (SIBLING) family of proteins

The protein encoded by APPL1 has been shown to be involved in the regulation of cell proliferation

The protein encoded by this gene functions as a receptor or| with Frizzled| a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade

Huntingtin(Phospho Ser421) Polyclonal Antibody, 100ul Vector Construction This factor undergoes multiple processingHuntingtin is a disease gene linked to Huntington's disease, a neurodegenerative disorder characterized by loss of striatal neurons. This is thought to be caused by an expanded, unstable trinucleotide repeat in the huntingtin gene, which translates as a polyglutamine repeat in the protein product. A fairly broad range of trinucleotide repeats (9 35) has been identified in normal controls, and repeat numbers in excess of 40 have been described as

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