NEIL3 Polyclonal Antibody, 50ul Culture Media The gamma 3 chain is

The gamma 3 chain is broadly expressed in skin

mutations in either gene may contribute to these disorders

The encoded protein has similarity to yeast Sec23p component of COPII

This protein is associated with the nuclear matrix in perichromatin fibrils and

This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12

NEIL3 Polyclonal Antibody, 50ul Culture Media The gamma 3 chain isNEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.