Erbin Rabbit Polyclonal Antibody, 50ul[BT-AP09695] Deep Well Plates TPD52L1 (D53)

TPD52L1 (D53)

Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy| an autosomal recessive disorder of unregulated and high insulin secretion

May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane

and protein-protein interactions

reducing the research

Erbin Rabbit Polyclonal Antibody, 50ul[BT-AP09695] Deep Well Plates TPD52L1 (D53)This gene is a member of the leucine rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.