BCL2L12 Polyclonal Antibody, 20ul Enzymes Also removes gene-encoded polyglutamates from
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BCL2L12 Polyclonal Antibody, 20ul Enzymes Also removes gene-encoded polyglutamates fromBCL2L12 (BCL2 like 12) encodes a member of a family of proteins containing a Bcl 2 homology domain 2 (BH2). The encoded protein is an anti apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of BCL2L12 has been detected in a number of different cancers. There is a pseudogene for BCL2L12 on chromosome
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