FBW1A Rabbit Polyclonal Antibody, 50ul Molecular Weight Markers The N-terminal C2 domain associates

The N-terminal C2 domain associates with lipid membranes and mediates its regulation by presenting the active site to its substrate in response to elevations of cytosolic Ca(2+)

The protein encoded by this gene includes a C2 domain| which is known to mediate homodimerization in the related WWC1 gene product

Mutations in this gene may be associated with Hirschsprung disease and Tourette syndrome

and may act as a DNA unwinding enzyme

The RAB6-interacting golgin may function in the secretory pathway

FBW1A Rabbit Polyclonal Antibody, 50ul Molecular Weight Markers The N-terminal C2 domain associatesThis gene encodes a member of the F box protein family which is characterized by an approximately 40 amino acid motif the F box. The F box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1 cullin F box) which function in phosphorylation dependent ubiquitination. The F box proteins are divided into 3 classes: Fbws containing WD 40 domains Fbls containing leucine rich repeats and Fbxs containing either