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p107 Polyclonal Antibody, 50ul RNA Synthesis Depletion of this protein in

SKU: 5286070745

4.1
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p107 Polyclonal Antibody, 50ul RNA Synthesis Depletion of this protein inThe protein encoded by RBL1 (RB transcriptional corepressor like 1) is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex

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Description

Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis

The encoded transmembrane protein binds to SEMA3C protein {sema domain

Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation

Alternate splicing of this gene results in at least two isoforms that localize to the centrosome and the Golgi apparatus

resulting in its dissociation from eIF4E and activation of mRNA translation

p107 Polyclonal Antibody, 50ul RNA Synthesis Depletion of this protein inThe protein encoded by RBL1 (RB transcriptional corepressor like 1) is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex

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