Rat Tissue-type Plasminogen Activator, TPA ELISA Kit, 96T Lysosome Several transcript variants encoding different

Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene

Binds to cyclins A and E

NTT5 shows structural characteristics of an Na(+)- and Cl(-)-dependent neurotransmitter transporter

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It dilates a variety of vessels including the coronary

Rat Tissue-type Plasminogen Activator, TPA ELISA Kit, 96T Lysosome Several transcript variants encoding differentConverts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg Val bond in plasminogen. By controlling plasmin mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. During oocyte activation, plays a role in cortical granule reaction in the zona reaction, which contributes to the block to polyspermy (PubMed: 1515147).