CD45 Monoclonal Antibody(12A9), 20ul Metabolic enzymes The deficient mice exhibited defects

The deficient mice exhibited defects in early differentiation of T and B lymphocytes

Loss of expression of the related gene in mouse affects coat and eye pigmentation

thus linking suppression of apoptosis to metastasis

It may also function as a redox-sensitive chaperone

A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility

CD45 Monoclonal Antibody(12A9), 20ul Metabolic enzymes The deficient mice exhibited defectsThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been