p53(Phospho Thr81) Polyclonal Antibody, 100ul Molecular Sciences Mutations in this gene have

Mutations in this gene have been associated with oculodentodigital dysplasia

Cadherins mediate cell-cell binding in a homophilic manner

and is induced by transforming growth factor-beta (TGF-beta) to repress TGF-beta receptor II gene expression

This gene may be associated with tumor progression

due to the N-terminal 1-49 amino acid sequence that could be cut down

p53(Phospho Thr81) Polyclonal Antibody, 100ul Molecular Sciences Mutations in this gene haveThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.