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CD32 Polyclonal Antibody, 50ul[BT-AP07393] Plasmid Preparation Mutations in this gene have

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CD32 Polyclonal Antibody, 50ul[BT-AP07393] Plasmid Preparation Mutations in this gene haveThe Fc fragment of IgG receptor IIb encoded by FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.

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Description

Mutations in this gene have been associated with autosomal recessive non-syndromic deafness and Usher Syndrome

and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies

for 50mLx16

This gene is upregulated by interferon-gamma and encodes a protein that is a member of the AGP11/GTPBP1 family of GTP-binding proteins

Specifically

CD32 Polyclonal Antibody, 50ul[BT-AP07393] Plasmid Preparation Mutations in this gene haveThe Fc fragment of IgG receptor IIb encoded by FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.

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