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EP-CAM Polyclonal Antibody, 100ul[BT-AP02987] Liquid Storage Consumables Take the risk and seize

SKU: 51184121610

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EP-CAM Polyclonal Antibody, 100ul[BT-AP02987] Liquid Storage Consumables Take the risk and seizeEPCAM encodes a carcinoma associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in EPCAM result in congenital tufting enteropathy.

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This gene also has pseudogenes on chromosomes 9

A neurturin mutation has been described in a family with Hirschsprung Disease

This gene encodes a protein that is highly similar to the yeast SIN1 protein| a stress-activated protein kinase

Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms

EP-CAM Polyclonal Antibody, 100ul[BT-AP02987] Liquid Storage Consumables Take the risk and seizeEPCAM encodes a carcinoma associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in EPCAM result in congenital tufting enteropathy.

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