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IGF-IR Polyclonal Antibody, 50ul[BT-AP04398] Cryopreservation This gene encodes a member

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IGF-IR Polyclonal Antibody, 50ul[BT-AP04398] Cryopreservation This gene encodes a memberIGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms

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Description

This gene encodes a member of the MOZ

Gene Ontology (GO) annotations related to this gene include transcription factor activity

cofactor:Binds 2 cobalt ions per subunit

This gene encodes a transmembrane protein that is necesssary for mechanotransduction in cochlear hair cells of the inner ear

and it has a potential role in renovascular hypertension which has known correlations to renal failure

IGF-IR Polyclonal Antibody, 50ul[BT-AP04398] Cryopreservation This gene encodes a memberIGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms

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