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NKAP Polyclonal Antibody, 20ul Cell Biology It encodes a heparin-binding protein

SKU: 50997758973

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NKAP Polyclonal Antibody, 20ul Cell Biology It encodes a heparin-binding proteinThis gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which

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Description

It encodes a heparin-binding protein

Defects in HSPB1 are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN)

Defects in this gene are a cause of childhood cancer retinoblastoma (RB)

it is seen within the basement membrane of the dermal-epidermal junction at points of nerve penetration

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NKAP Polyclonal Antibody, 20ul Cell Biology It encodes a heparin-binding proteinThis gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which

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