CD55 Polyclonal Antibody, 100ul[BT-AP02140] Human Genome Knockout Libraries Alternate splicing results in multiple

Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing

|Contains 1 collagen IV NC1 (C-terminal non-collagenous) domain

Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis

These genes are characterized by several distinct features

Alternately spliced transcript variants have been observed for this gene

CD55 Polyclonal Antibody, 100ul[BT-AP02140] Human Genome Knockout Libraries Alternate splicing results in multipleCortactin, encoded by CTTN gene (formerly EMS1), was originally identified as a substrate of the Src kinase. It is a cytoskeletal protein that interacts with F actin and Arp2 3 complex and plays an important role in regulation of actin assembly and cytoskeleton dynamics. Overexpression of cortactin increases cell migration, and is thought to contribute to the invasive phennotype of breast cancer and several other tumors. Three isoforms of cortactin