Rock-1 Polyclonal Antibody, 50ul[BT-AP07968] Variant Libraries Two transcript variants| only one

Two transcript variants| only one of them protein-coding| have been found for this gene

and is present only in striated muscles

May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions

These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation

Specification: 1

Rock-1 Polyclonal Antibody, 50ul[BT-AP07968] Variant Libraries Two transcript variants| only oneROCK1 encodes a protein serine threonine kinase that is activated when bound to the GTP bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP bound form and the active GTP bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor.