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Rb(Phospho Ser811) Polyclonal Antibody, 20ul Micro Centrifuge Tubes Members of this family contain

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Rb(Phospho Ser811) Polyclonal Antibody, 20ul Micro Centrifuge Tubes Members of this family containThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

Members of this family contain zinc-finger and bZIP DNA-binding domains

congenital heart disease

a fibrinolytic enzyme

A related pseudogene has been defined on chromosome 16

ADAMTS family members share several distinct protein modules

Rb(Phospho Ser811) Polyclonal Antibody, 20ul Micro Centrifuge Tubes Members of this family containThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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