PAPP2 Polyclonal Antibody, 20ul Peripheral Blood Separation Tube An important paralog of this

An important paralog of this gene is GPR162

It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway

This gene is expressed primarily in the placenta and ovarian granulosa cells

It is located in the cytoplasm

In mouse| a similar pattern of expression was found

PAPP2 Polyclonal Antibody, 20ul Peripheral Blood Separation Tube An important paralog of thisThis gene encodes a member of the pappalysin family of metzincin metalloproteinases. The encoded protein cleaves insulin like growth factor binding protein 5 and is thought to be a local regulator of insulin like growth factor (IGF) bioavailability. Alternative splicing results in multiple transcript variants.