DAAM1 Polyclonal Antibody, 100ul Nucleic Acid Extraction Mutations in this gene are

Mutations in this gene are associated with type II autosomal recessive Alport syndrome (hereditary glomerulonephropathy) and with familial benign hematuria (thin basement membrane disease)

May play a role as a negative regulator of cell growth

also known as C5a receptor (C5aR)

which may contribute to its ability to reduce the tumorigenic phenotype in cells

An important paralog of this gene is BECN1

DAAM1 Polyclonal Antibody, 100ul Nucleic Acid Extraction Mutations in this gene areCell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt