PTEN(Phospho Ser380/T382/T383) Polyclonal Antibody, 20ul Shaker&Mixing This protein contains a Guanine

This protein contains a Guanine nucleotide exchange factor (GEF) domain which is necessary for its role in growth and differentiation

q12) with the pleiomorphic adenoma gene 1

Lys-29 and Lys-48-linked ubiquitin chains (in vitro) (PubMed: 24724799)

GO annotations related to this gene include G-protein coupled receptor activity andtransmembrane signaling receptor activity

and it has been determined that the diseased allele contains 40-83 CAG repeats

PTEN(Phospho Ser380/T382/T383) Polyclonal Antibody, 20ul Shaker&Mixing This protein contains a GuanineThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide