CART Polyclonal Antibody, 20ul Human Genome Knockout Libraries Fibroblast growth factor 12 encoded

Fibroblast growth factor 12 encoded by FGF12 is a member of the fibroblast growth factor (FGF) family

an autosomal recessive disorder characterized by conjugated hyperbilirubinemia

Defects in this gene are a cause of familial hypercholanemia (FHCA)

but the full-length nature for most of them has not been determined

Contains 4 fibronectin type-III domains

CART Polyclonal Antibody, 20ul Human Genome Knockout Libraries Fibroblast growth factor 12 encodedThis gene encodes a preproprotein that is proteolytically processed to generate multiple biologically active peptides. These peptides play a role in appetite, energy balance, maintenance of body weight, reward and addiction, and the stress response. Expression of a similar gene transcript in rodents is upregulated following administration of cocaine and amphetamine. Mutations in this gene are associated with susceptibility to obesity in humans.