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GAP-43 Monoclonal Antibody(Mix), 100ul Reservoirs The vitamin K-dependent protein C

SKU: 49306191103

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GAP-43 Monoclonal Antibody(Mix), 100ul Reservoirs The vitamin K-dependent protein CThe protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

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Description

The vitamin K-dependent protein C is cleaved to its activated form by the thrombin-thrombomodulin complex

which regulates its nuclear matrix and chromatin association

|PTM:N-glycosylated

A similar protein in mouse is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signaling pathway transcription factor recombining binding protein J

Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms

GAP-43 Monoclonal Antibody(Mix), 100ul Reservoirs The vitamin K-dependent protein CThe protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

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